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Article

Investigation of the association between Rho/Rho-kinase gene polymorphisms and systemic sclerosis.

Rheumatology international - 1 Mar 2016

Pehlivan Yavuz, Yolbas Servet, Cetin Gozde Yıldırım, Alibaz-Oner Fatma, Cagatay Yonca, Yilmaz Neslihan, Oztuzcu Serdar, Donmez Salim, Ozgen Metin, Koca Suleyman Serdar, Pamuk Omer Nuri, Sayarlıoglu Mehmet, Kisacik Bunyamin, Direskeneli Haner, Demiryurek Abdullah Tuncay, Onat Ahmet Mesut

Abstract excerpt

Systemic sclerosis (SSc) is a disease characterized by inflammation, vascular abnormalities and fibrosis. The role of Rho/Rho-kinase pathway was demonstrated in the pathogenesis of fibrosis, inflammation and vascular abnormalities. This study was aimed to investigate the relation between SSc and Rho/Rho-kinase gene polymorphisms. The study included 339 patients with SSc and 302 healthy subjects who were...

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PMID: 26615410
DOI: 10.1007/s00296-015-3400-4

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ROCK1
ROCK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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