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Article

Estrogen receptor gene polymorphism in Japanese patients with multiple sclerosis.

Journal of the neurological sciences - 1 Oct 2000

Niino M, Kikuchi S, Fukazawa T, Yabe I, Tashiro K

Abstract excerpt

Estrogen has been reported to have immunosuppressive functions, and to inhibit the progression of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS). Since estrogen shows its biological effects via estrogen receptors (ER), we investigate the possible role of ER genes (ERG) in the pathogenesis of MS. PvuII and XbaI polymorphisms in ERG were detected by PCR-RFLP from the DNA...

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Source

Identifiers

PMID: 11054488
DOI: 10.1016/s0022-510x(00)00381-6

Genes

ERG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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