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Article

Base excision repair genes and risk of lung cancer among San Francisco Bay Area Latinos and African-Americans.

Carcinogenesis - 1 Jan 2009

Chang Jeffrey S, Wrensch Margaret R, Hansen Helen M, Sison Jennette D, Aldrich Melinda C, Quesenberry Charles P, Seldin Michael F, Kelsey Karl T, Wiencke John K

Abstract excerpt

Base excision repair (BER) is the primary DNA damage repair mechanism for repairing small base lesions resulting from oxidation and alkylation damage. This study examines the association between 24 single-nucleotide polymorphisms (SNPs) belonging to five BER genes (XRCC1, APEX1, PARP1, MUTYH and OGG1) and lung cancer among Latinos (113 cases and 299 controls) and African-Americans (255 cases and 280 controls)....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19029194
DOI: 10.1093/carcin/bgn261
PMCID: PMC2722143

Genes

XRCC1
APEX1
MUTYH
OGG1
PARP1

Variants

rs25487

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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