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Article

Genetic polymorphism of XRCC1 and lung cancer risk among African-Americans and Caucasians.

Lung cancer (Amsterdam, Netherlands) - 1 Dec 2001

David-Beabes G L, London S J

Abstract excerpt

Reduced DNA repair capacity may influence susceptibility to lung cancer. XRCC1 plays an important role in base excision repair and in rejoining DNA strand breaks. In the XRCC1 gene, two common polymorphisms induce amino acid changes in codon 194 and codon 399 and correlate with levels of genotoxi...

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Identifiers

PMID: 11714530
DOI: 10.1016/s0169-5002(01)00256-2

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11714530-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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