Article
DNA Base-Excision Repair Genes OGG1 and NTH1 in Brazilian Lung Cancer Patients.
Molecular diagnosis & therapy - 1 Dec 2015
Couto Patricia G, Bastos-Rodrigues Luciana, Carneiro Juliana G, Guieiro Fernanda, Bicalho Maria Aparecida, Leidenz Franciele B, Bicalho Ana J, Friedman Eitan, De Marco Luiz
Abstract excerpt
INTRODUCTION: Lung cancer is the leading global cause of cancer-related mortality and is associated with poor prognosis. To improve survival rates of lung cancer patients, better understanding of tumorigenic mechanisms is necessary, which may lead to development of new therapeutic strategies. The hOGG1 and NTH1 genes act in the DNA BER repair pathway and their involvement in lung cancer pathogenesis has been...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
