Article
The influence of the genetic variant within miRNA-binding site in estrogen receptor alpha gene on the risk of breast cancer in postmenopausal women on hormone replacement therapy.
Cancer biomarkers : section A of Disease markers - 1 Jan 2010
Cerne Jasmina-Ziva, Gersak Ksenija, Novakovic Srdjan
Abstract excerpt
OBJECTIVE: The aim of the study was to analyze the impact of the rs2747648 genetic variant in the estrogen receptor alpha (ER1) gene affecting a putative miR-453-binding site on the risk of breast cancer in postmenopausal women. Furthermore, we examined if the risk changes in a subset of women on hormone replacement therapy (HRT). PATIENTS AND METHODS: We studied 530 breast cancer cases and 270 controls of the...
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