Article
Validation of associations between ESR1 variants and breast cancer risk in Chinese cohorts.
Genetics and molecular research : GMR - 15 Jul 2016
Li X, Yao G Y, Li F X, Qiu Y R, Yang X X
Abstract excerpt
Estrogen receptor-a (ER) protein plays a key role in breast carcinogenesis, and common genetic variants in the corresponding gene locus have been associated with breast cancer risk in different populations. Here, we analyzed estrogen receptor 1 (ESR1) associations in two hospital-based studies of patients from the south of China. Three single-nucleotide polymorphisms (SNPs; rs3757318, rs2046210, and rs3734805) in...
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