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Article

Transgenic model of cardiac rhabdomyosarcoma formation.

The Journal of thoracic and cardiovascular surgery - 1 Nov 2008

Köbbert Christiane, Möllmann Christa, Schäfers Michael, Hermann Sven, Baba Hideo A, Hoffmeier Andreas, Breithardt Günter, Scheld Hans H, Weissen-Plenz Gabriele, Sindermann Jürgen R

Abstract excerpt

OBJECTIVES: Cardiac rhabdomyosarcomas are rare, and the pathogenesis of this detrimental disease is widely unknown. Most data are obtained from case reports or small series, and models for systematic pathogenetic studies are lacking. We aimed to establish a transgenic mouse model of cardiac rhabdomyosarcoma formation. METHODS: Standard techniques were used to construct a minigene comprised of the 5' region of the...

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PMID: 19026800
DOI: 10.1016/j.jtcvs.2008.04.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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