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Article

A mouse model of cardiac rhabdomyoma generated by loss of Tsc1 in ventricular myocytes.

Human molecular genetics - 1 Feb 2005

Meikle Lynsey, McMullen Julie R, Sherwood Megan C, Lader Alan S, Walker Victoria, Chan Jennifer A, Kwiatkowski David J

Abstract excerpt

Tuberous sclerosis is a hamartoma syndrome due to mutations in TSC1 or TSC2 in which cardiac rhabdomyomas are seen in approximately 60% of patients. These lesions have an unusual natural history as they are usually most prominent immediately after birth and spontaneously resolve in most cases. To...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15601645
DOI: 10.1093/hmg/ddi039

Genes

TSC1
TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15601645-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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