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Article

Transgenic mice carrying the human beta 2-adrenergic receptor gene with its own promoter overexpress beta 2-adrenergic receptors in liver.

European journal of biochemistry - 15 Oct 1996

André C, Erraji L, Gaston J, Grimber G, Briand P, Guillet J G

Abstract excerpt

Up to now, transgenic mice models created to study the physiological impact of alterations in the human beta-adrenoceptor system have only focused on cardiac tissues and carried hybrid transgenes with strong cardiac promoters. We have developed a transgenic mouse strain (F28) carrying the human beta 2-adrenoceptor gene with its natural promoter region with the aim of producing a model that more closely reproduces...

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PMID: 8917438
DOI: 10.1111/j.1432-1033.1996.00417.x

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