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Article

Autoacetylation regulates P/CAF nuclear localization.

The Journal of biological chemistry - 16 Jan 2009

Blanco-García Noemí, Asensio-Juan Elena, de la Cruz Xavier, Martínez-Balbás Marian A

Abstract excerpt

Acetylation is a posttranslational modification that alters the biological activities of proteins by affecting their association with other proteins or DNA, their catalytic activities, or their subcellular distribution. The acetyltransferase P/CAF is autoacetylated and acetylated by p300 in vivo. P/CAF autoacetylation is an intramolecular or intermolecular event. Intramolecular acetylation targets five lysines...

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Topics

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Share to Acetylation
Share to Active Transport, Cell Nucleus
Share to Cytoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histone Acetyltransferases

Share to NIH 3T3 Cells

Share to Nuclear Localization Signals

Share to p300-CBP Transcription Factors

Share to Protein Processing, Post-Translational

Source

Identifiers

PMID: 19015268
DOI: 10.1074/jbc.M806075200

Genes

HDAC1
HDAC2
HDAC3
HDAC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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