Article

A phospho-regulated signal motif determines subcellular localization of α-TAT1 for dynamic microtubule acetylation

2020-09-23

Abstract excerpt

Spatiotemporally dynamic microtubule acetylation underlies diverse physiological events ranging from cell migration to intracellular trafficking, autophagy and viral infections. Despite its ubiquity, the molecular mechanisms that regulate the sole microtubule acetylating agent, α-tubulin N-acetyltransferase 1 (α-TAT1) remain obscure. Here we report that dynamic intracellular localization of α-TAT1 unexpectedly det...

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Identifiers and source

Literature Corpus work: 26ce068c-bb14-5182-9bea-f41c0ea37490
DOI: 10.1101/2020.09.23.310235

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