Article
Possible role of transcriptional coactivator P/CAF and nuclear acetylation in calcium-induced keratinocyte differentiation.
The Journal of biological chemistry - 8 Mar 2002
Kawabata Hisashi, Kawahara Ko-ichi, Kanekura Takuro, Araya Natsumi, Daitoku Hiroaki, Hatta Mitsutoki, Miura Naoki, Fukamizu Akiyoshi, Kanzaki Tamotsu, Maruyama Ikuro, Nakajima Toshihiro
Abstract excerpt
Several nuclear factors, called coactivators, such as CREB (cAMP response element binding protein)-binding protein (CBP) and p300/CBP associated factor (P/CAF), have intrinsic histone acetyltransferase (HAT) activity. Recent studies have shown that, in addition to histones, transcriptional regulatory molecules are also targets of HATs, and nuclear acetylation is thought to be involved in several biological...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.