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Article

Rapid telomere motions in live human cells analyzed by highly time-resolved microscopy

27 Oct 2008

Abstract excerpt

BACKGROUND: Telomeres cap chromosome ends and protect the genome. We studied individual telomeres in live human cancer cells. In capturing telomere motions using quantitative imaging to acquire complete high-resolution three-dimensional datasets every second for 200 seconds, telomere dynamics were systematically analyzed. RESULTS: The motility of individual telomeres within the same cancer cell nucleus was widely...

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Share to Epigenetics and DNA Methylation
Share to Nuclear Structure and Function
Share to Telomeres, Telomerase, and Senescence

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PMID: 19014413
DOI: 10.1186/1756-8935-1-4

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