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Controlled light exposure microscopy reveals dynamic telomere microterritories throughout the cell cycle

18 Dec 2008

Abstract excerpt

Telomeres are complex end structures that confer functional integrity and positional stability to human chromosomes. Despite their critical importance, there is no clear view on telomere organization in cycling human cells and their dynamic behavior throughout the cell cycle. We investigated spatiotemporal organization of telomeres in living human ECV-304 cells stably expressing telomere binding proteins TRF1 and...

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Share to Chromosomal and Genetic Variations
Share to Genomics and Chromatin Dynamics
Share to Telomeres, Telomerase, and Senescence

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PMID: 19097172
DOI: 10.1002/cyto.a.20699

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