Article
Serotonin transporter polymorphism is associated with increased apnea-hypopnea index in older adults.
International journal of geriatric psychiatry - 1 Mar 2014
Schröder Carmen M, Primeau Michelle M, Hallmayer Joachim F, Lazzeroni Laura C, Hubbard Jeffrey T, O'Hara Ruth
Abstract excerpt
RATIONALE: A functional polymorphism of the serotonin transporter gene (5-HTTLPR) has previously been related to upper airway pathology, but its contribution to obstructive sleep apnea (OSA), a highly prevalent sleep disorder in older adults, remains unclear. OBJECTIVES: We aimed to investigate the relationship between apnea-hypopnea index (AHI) and genetic variations in the promoter region of the 5-HTTLPR in...
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