Article
Functional properties of mixed cystic fibrosis and normal bronchial epithelial cell cultures.
American journal of respiratory cell and molecular biology - 1 Jun 2009
Dannhoffer Luc, Blouquit-Laye Sabine, Regnier Agathe, Chinet Thierry
Abstract excerpt
Cystic fibrosis (CF) airway epithelia exhibit altered Cl(-) and Na(+) transport properties and increased IL-8 secretion. In the present study, we examined whether a small proportion of cells with a normal phenotype could normalize the ion transport and IL-8 secretion properties of a CF airway epithelial cell layer. We obtained three types of primary cultures of human bronchial epithelial cells: one composed of...
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