Article
Development of cystic fibrosis and noncystic fibrosis airway cell lines.
American journal of physiology. Lung cellular and molecular physiology - 1 May 2003
Zabner Joseph, Karp Phil, Seiler Michael, Phillips Stacia L, Mitchell Calista J, Saavedra Mimi, Welsh Michael, Klingelhutz Aloysius J
Abstract excerpt
In this study, we utilized the reverse transcriptase component of telomerase, hTERT, and human papillomavirus type 16 (HPV-16) E6 and E7 genes to transform normal and cystic fibrosis (CF) human airway epithelial (HAE) cells. One cell line, designated NuLi-1 (normal lung, University of Iowa), was derived from HAE of normal genotype; three cell lines, designated CuFi (cystic fibrosis, University of Iowa)-1, CuFi-3,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
