Article

Development of a multicellular co-culture model of normal and cystic fibrosis human airways in vitro

2012-01-01

Abstract excerpt

Cystic fibrosis (CF) is the most common lethal inherited disease among Caucasians and arises due to mutations in a chloride channel, called cystic fibrosis transmembrane conductance regulator. A hallmark of this disease is the chronic bacterial infection of the airways, which is usually, associated with pathogens such as Pseudomonas aeruginosa, S. aureus and recently becoming more prominent, B. cepacia. The excess...

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Literature Corpus work: 1bae7a59-173a-5569-8eeb-bc1ad07d6526
DOI: 10.48780/publications.aston.ac.uk.00016494

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