Article
Epithelial cell specific properties and genetic complementation in a delta F508 cystic fibrosis nasal polyp cell line.
In vitro cellular & developmental biology. Animal - 1 Sept 1995
Kunzelmann K, Lei D C, Eng K, Escobar L C, Koslowsky T, Gruenert D C
Abstract excerpt
Analysis of vectorial ion transport and protein trafficking in transformed cystic fibrosis (CF) epithelial cells has been limited because the cells tend to lose their tight junctions with multiple subcultures. To elucidate ion transport and protein trafficking in CF epithelial cells, a polar cell line with apical and basolateral compartments will facilitate analysis of the efficacy of different gene therapy...
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