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Article

Characterization of the mycobacterial NER system reveals novel functions of the uvrD1 helicase.

Journal of bacteriology - 1 Jan 2009

Güthlein Carolin, Wanner Roger M, Sander Peter, Davis Elaine O, Bosshard Martin, Jiricny Josef, Böttger Erik C, Springer Burkhard

Abstract excerpt

In this study, we investigated the role of the nucleotide excision repair (NER) pathway in mycobacterial DNA repair. Mycobacterium smegmatis lacking the NER excinuclease component uvrB or the helicase uvrD1 gene and a double knockout lacking both genes were constructed, and their sensitivities to a series of DNA-damaging agents were analyzed. As anticipated, the mycobacterial NER system was shown to be involved...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19011038
DOI: 10.1128/JB.00216-08
PMCID: PMC2620815

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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