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Article

Base excision and nucleotide excision repair pathways in mycobacteria.

Tuberculosis (Edinburgh, Scotland) - 1 Nov 2011

Kurthkoti Krishna, Varshney Umesh

Abstract excerpt

About a third of the human population is estimated to be infected with Mycobacterium tuberculosis. The bacterium displays an excellent adaptability to survive within the host macrophages. As the reactive environment of macrophages is capable of inducing DNA damage, the ability of the pathogen to safeguard its DNA against the damage is of paramount significance for its survival within the host. Analysis of the...

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PMID: 21764637
DOI: 10.1016/j.tube.2011.06.005

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