Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA ligase C1 mediates the LigD-independent nonhomologous end-joining pathway of Mycobacterium smegmatis.

Journal of bacteriology - 1 Oct 2014

Bhattarai Hitesh, Gupta Richa, Glickman Michael S

Abstract excerpt

Nonhomologous end joining (NHEJ) is a recently described bacterial DNA double-strand break (DSB) repair pathway that has been best characterized for mycobacteria. NHEJ can religate transformed linear plasmids, repair ionizing radiation (IR)-induced DSBs in nonreplicating cells, and seal I-SceI-induced chromosomal DSBs. The core components of the mycobacterial NHEJ machinery are the DNA end binding protein Ku and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to DNA, Bacterial
Share to DNA-Directed DNA Polymerase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA End-Joining Repair

Share to DNA Ligase ATP

Share to DNA Ligases

Share to Mutation

Share to Mycobacterium smegmatis

Source

Open in PubMed Open full text

Identifiers

PMID: 24957619
DOI: 10.1128/JB.01832-14
PMCID: PMC4187670

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA ligase C1 mediates the LigD-independent nonhomologous end-joining pathway of Mycobacterium smegmatis.PMID 24957619Read ↗

The pathways and outcomes of mycobacterial NHEJ depend on the structure of the broken DNA ends.Semantic proximity Read ↗

Mycobacterial Ku and ligase proteins constitute a two-component NHEJ repair machine.Semantic proximity Read ↗

Mechanism of nonhomologous end-joining in mycobacteria: a low-fidelity repair system driven by Ku, ligase D and ligase C.Semantic proximity Read ↗

Mycobacterial nonhomologous end joining mediates mutagenic repair of chromosomal double-strand DNA breaks.Semantic proximity Read ↗

Crystal structure and nonhomologous end-joining function of the ligase component of Mycobacterium DNA ligase D.Semantic proximity Read ↗

Characterization of the roles of the catalytic domains of Mycobacterium tuberculosis ligase D in Ku-dependent error-prone DNA end joining.Semantic proximity Read ↗

Characterization of the mycobacterial NER system reveals novel functions of the uvrD1 helicase.Semantic proximity Read ↗

Evaluation of NAD(+) -dependent DNA ligase of mycobacteria as a potential target for antibiotics.Semantic proximity Read ↗

NHEJ protects mycobacteria in stationary phase against the harmful effects of desiccation.Semantic proximity Read ↗

Genetic interactions between BLM and DNA ligase IV in human cells.Semantic proximity Read ↗

DNA repair systems and the pathogenesis of <i>Mycobacterium tuberculosis</i>: varying activities at different stages of infectionSemantic proximity Read ↗

Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.