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Article

The biological and structural characterization of Mycobacterium tuberculosis UvrA provides novel insights into its mechanism of action.

Nucleic acids research - 1 Sept 2011

Rossi Franca, Khanduja Jasbeer Singh, Bortoluzzi Alessio, Houghton Joanna, Sander Peter, Güthlein Carolin, Davis Elaine O, Springer Burkhard, Böttger Erik C, Relini Annalisa, Penco Amanda, Muniyappa K, Rizzi Menico

Abstract excerpt

Mycobacterium tuberculosis is an extremely well adapted intracellular human pathogen that is exposed to multiple DNA damaging chemical assaults originating from the host defence mechanisms. As a consequence, this bacterium is thought to possess highly efficient DNA repair machineries, the nucleotide excision repair (NER) system amongst these. Although NER is of central importance to DNA repair in M. tuberculosis,...

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Identifiers

PMID: 21622956
DOI: 10.1093/nar/gkr271
PMCID: PMC3167621

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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