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Article

The C1 and C2 domains target human type 6 adenylyl cyclase to lipid rafts and caveolae.

Cellular signalling - 1 Feb 2009

Thangavel Muthusamy, Liu Xiaoqiu, Sun Shu Qiang, Kaminsky Joseph, Ostrom Rennolds S

Abstract excerpt

Previous data has shown that adenylyl cyclase type 6 (AC6) is expressed principally in lipid rafts or caveolae of cardiac myocytes and other cell types while certain other isoforms of AC are excluded from these microdomains. The mechanism by which AC6 is localized to lipid rafts or caveolae is unknown. In this study, we show AC6 is localized in lipid rafts of COS-7 cells (expressing caveolin-1) and in HEK-293...

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Share to Adenylyl Cyclases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19007881
DOI: 10.1016/j.cellsig.2008.10.017
PMCID: PMC2630290

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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