Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dimerization of mammalian adenylate cyclases.

European journal of biochemistry - 1 Jan 2002

Gu Chen, Cali James J, Cooper Dermot M F

Abstract excerpt

Mammalian adenylate cyclases are predicted to possess complex topologies, comprising two cassettes of six transmembrane-spanning motifs followed by a cytosolic, catalytic ATP-binding domain. Recent studies have begun to provide insights on the tertiary assembly of these proteins; crystallographic analysis has revealed that the two cytosolic domains dimerize to form a catalytic core, while more recent biochemical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenylyl Cyclases
Share to Dimerization
Share to Energy Transfer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorescence

Share to Green Fluorescent Proteins

Share to HeLa Cells

Share to Luminescent Proteins

Share to Precipitin Tests

Source

Identifiers

PMID: 11856299
DOI: 10.1046/j.0014-2956.2001.02708.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dimerization of mammalian adenylate cyclases.PMID 11856299Read ↗

Guanylate cyclase-activating proteins: structure, function, and diversitySemantic proximity Read ↗

Isoform Specific Regulation of Adenylyl Cyclase 5 by GβγSemantic proximity Read ↗

Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia.Semantic proximity Read ↗

Isoforms of mammalian adenylyl cyclase: multiplicities of signaling.Semantic proximity Read ↗

Comparative electrostatic analysis of adenylyl cyclase for isoform dependent regulation properties.Semantic proximity Read ↗

Disease association of cyclase-associated protein (CAP): Lessons from gene-targeted mice and human genetic studiesSemantic proximity Read ↗

Intermolecular interactions between dimeric calcium-sensing receptor monomers are important for its normal function.Semantic proximity Read ↗

NMR Structure of Retinal Guanylate Cyclase Activating Protein 5 (GCAP5) with R22A Mutation That Abolishes Dimerization and Enhances Cyclase Activation.Semantic proximity Read ↗

Molecular properties of human guanylate cyclase-activating protein 2 (GCAP2) and its retinal dystrophy-associated variant G157R.Semantic proximity Read ↗

Evidence that prokineticin receptor 2 exists as a dimer in vivo.Semantic proximity Read ↗

Adenylyl cyclase 9 as a molecular scaffold to dissect the regulatory mechanisms of membrane adenylyl cyclasesSemantic proximity Read ↗

Activation of the diguanylate cyclase PleD by phosphorylation-mediated dimerization.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.