Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Saccharomyces cerevisiae gene CDC40/PRP17 controls cell cycle progression through splicing of the ANC1 gene.

Nucleic acids research - 1 Jan 2004

Dahan Orna, Kupiec Martin

Abstract excerpt

The timing of events in the cell cycle is of crucial importance, as any error can lead to cell death or cancerous growth. This accurate timing is accomplished through the activation of specific CDC genes. Mutations in the CDC40/PRP17 gene cause cell cycle arrest at the G2/M stage. It was previously found that the CDC40 gene encodes a pre-mRNA splicing factor, which participates in the second step of the splicing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Copper
Share to Drug Resistance, Fungal
Share to RNA, Fungal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to RNA Precursors

Share to RNA Splice Sites

Share to RNA Splicing

Share to RNA Splicing Factors

Share to Transcription Factor TFIID

Source

Open in PubMed Open full text

Identifiers

PMID: 15133121
DOI: 10.1093/nar/gkh574
PMCID: PMC419462

Genes

CDC40

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Saccharomyces cerevisiae gene CDC40/PRP17 controls cell cycle progression through splicing of the ANC1 gene.PMID 15133121Read ↗

Extensive genetic interactions between PRP8 and PRP17/CDC40, two yeast genes involved in pre-mRNA splicing and cell cycle progression.Semantic proximity Read ↗

Dependence of pre-mRNA introns on PRP17, a non-essential splicing factor: implications for efficient progression through cell cycle transitions.Semantic proximity Read ↗

Mutations in genes of Saccharomyces cerevisiae encoding pre-mRNA splicing factors cause cell cycle arrest through activation of the spindle checkpoint.Semantic proximity Read ↗

The Cdk inhibitors p25rum1 and p40SIC1 are functional homologues that play similar roles in the regulation of the cell cycle in fission and budding yeast.Semantic proximity Read ↗

The transcription factor Swi5 regulates expression of the cyclin kinase inhibitor p40SIC1.Semantic proximity Read ↗

A nuclear protein with sequence similarity to proteins implicated in human acute leukemias is important for cellular morphogenesis and actin cytoskeletal function in Saccharomyces cerevisiae.Semantic proximity Read ↗

Anc1, a protein associated with multiple transcription complexes, is involved in postreplication repair pathway in S. cerevisiae.Semantic proximity Read ↗

A connection between pre-mRNA splicing and the cell cycle in fission yeast: cdc28+ is allelic with prp8+ and encodes an RNA-dependent ATPase/helicase.Semantic proximity Read ↗

Prp4 Kinase Grants the License to Splice: Control of Weak Splice Sites during Spliceosome Activation.Semantic proximity Read ↗

Regulation of Cdc2p and Cdc13p is required for cell cycle arrest induced by defective RNA splicing in fission yeast.Semantic proximity Read ↗

Caenorhabditis elegans Aurora A kinase AIR-1 is required for postembryonic cell divisions and germline development.Semantic proximity Read ↗

Screens for extragenic mutations that fail to complement act1 alleles identify genes that are important for actin function in Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.