Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cripto localizes Nodal at the limiting membrane of early endosomes.

Science signaling - 11 Nov 2008

Blanchet Marie-Hélène, Le Good J Ann, Oorschot Viola, Baflast Stéphane, Minchiotti Gabriella, Klumperman Judith, Constam Daniel B

Abstract excerpt

Cripto is a glycosylphosphatidylinositol (GPI)-anchored co-receptor of Nodal and several other transforming growth factor-beta (TGF-beta) family ligands. It contains an epidermal growth factor (EGF)-like motif and a Cripto-FRL1-Cryptic (CFC) domain, which are conserved in a family of EGF-CFC prot...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chlorocebus aethiops
Share to Endosomes
Share to Activin Receptors, Type I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epidermal Growth Factor

Share to Intracellular Membranes

Share to Membrane Glycoproteins

Share to Neoplasm Proteins

Share to Nodal Protein

Source

Identifiers

PMID: 19001664
DOI: 10.1126/scisignal.1165027

Genes

EGF
GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19001664-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cripto localizes Nodal at the limiting membrane of early endosomes.PMID 19001664Read ↗

Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway.Semantic proximity Read ↗

A GPI processing phospholipase A2, PGAP6, modulates Nodal signaling in embryos by shedding CRIPTO.Semantic proximity Read ↗

Non-cell-autonomous role for Cripto in axial midline formation during vertebrate embryogenesis.Semantic proximity Read ↗

Cripto promotes A-P axis specification independently of its stimulatory effect on Nodal autoinduction.Semantic proximity Read ↗

Nodal-dependent Cripto signaling promotes cardiomyogenesis and redirects the neural fate of embryonic stem cells.Semantic proximity Read ↗

Cripto-1 Activates Nodal- and ALK4-Dependent and -Independent Signaling Pathways in Mammary Epithelial CellsSemantic proximity Read ↗

The pro-domain of the zebrafish Nodal-related protein Cyclops regulates its signaling activities.Semantic proximity Read ↗

Nodal·Gdf1 Heterodimers with Bound Prodomains Enable Serum-independent Nodal Signaling and Endoderm DifferentiationSemantic proximity Read ↗

Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion.Semantic proximity Read ↗

Molecular evolution of the EGF-CFC protein family.Semantic proximity Read ↗

The carboxy terminal coiled-coil modulates Orai1 internalization during meiosis.Semantic proximity Read ↗

Junctate is a Ca2+-sensing structural component of Orai1 and stromal interaction molecule 1 (STIM1).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.