Article
Whole-genome mutational biases in bacteria.
Proceedings of the National Academy of Sciences of the United States of America - 18 Nov 2008
Lind Peter A, Andersson Dan I
Abstract excerpt
A fundamental biological question is what forces shape the guanine plus cytosine (GC) content of genomes. We studied the specificity and rate of different mutational biases in real time in the bacterium Salmonella typhimurium under conditions of strongly reduced selection and in the absence of the major DNA repair systems involved in repairing common spontaneous mutations caused by oxidized and deaminated DNA...
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