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Article

Toward targeting B cell cancers with CD4+ CTLs: identification of a CD19-encoded minor histocompatibility antigen using a novel genome-wide analysis.

The Journal of experimental medicine - 24 Nov 2008

Spaapen Robbert M, Lokhorst Henk M, van den Oudenalder Kelly, Otterud Brith E, Dolstra Harry, Leppert Mark F, Minnema Monique C, Bloem Andries C, Mutis Tuna

Abstract excerpt

Some minor histocompatibility antigens (mHags) are expressed exclusively on patient hematopoietic and malignant cells, and this unique set of antigens enables specific targeting of hematological malignancies after human histocompatability leucocyte antigen (HLA)-matched allogeneic stem cell trans...

Read the complete abstract on PubMed

Topics

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Share to Antigens, CD19
Share to B-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD4-Positive T-Lymphocytes

Share to Histocompatibility Antigens Class II

Share to HLA Antigens

Share to Immunophenotyping

Share to Leukemia, B-Cell

Share to T-Lymphocytes, Cytotoxic

Source

Open in PubMed Open full text

Identifiers

PMID: 19001137
DOI: 10.1084/jem.20080713
PMCID: PMC2585855

Genes

SCT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19001137-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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