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Article

Exogenous brain-derived neurotrophic factor (BDNF) reverts phenotypic changes in the retinas of transgenic mice lacking the BDNF gene.

Investigative ophthalmology & visual science - 1 Mar 2009

Arango-González Blanca, Cellerino Alessandro, Kohler Konrad

Abstract excerpt

PURPOSE: The authors investigated the effect of brain-derived neurotrophic factor (BDNF) administration on the expression of Ca(2+)-binding proteins in the developing bdnf(-/-) mouse retina. METHODS: Intraocular injections of BDNF (0.5 microg) were applied on postnatal day (P) 11 bdnf(-/-) mice, and their effects were evaluated on P14. Neurons expressing Ca(2+)-binding protein were studied by immunohistochemistry...

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Source

Identifiers

PMID: 18997090
DOI: 10.1167/iovs.08-2244

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Exogenous brain-derived neurotrophic factor (BDNF) reverts phenotypic changes in the retinas of transgenic mice lacking the BDNF gene.PMID 18997090Read ↗

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