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Article

Recovery of deficient homologous recombination in Brca2-depleted mouse cells by wild-type Rad51 expression.

DNA repair - 1 Feb 2009

Lee Shauna A, Roques Céline, Magwood Alissa C, Masson Jean-Yves, Baker Mark D

Abstract excerpt

The BRCA2 tumor suppressor is important in maintaining genomic stability. BRCA2 is proposed to control the availability, cellular localization and DNA binding activity of the central homologous recombination protein, RAD51, with loss of BRCA2 resulting in defective homologous recombination. Nevertheless, the roles of BRCA2 in regulating RAD51 and how other proteins implicated in RAD51 regulation, such as RAD52...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18992372
DOI: 10.1016/j.dnarep.2008.10.002

Genes

BRCA2
RAD51
RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Recovery of deficient homologous recombination in Brca2-depleted mouse cells by wild-type Rad51 expression.PMID 18992372Read ↗

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