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Article

Mechanistic insight into the ribosome biogenesis functions of the ancient protein KsgA.

Molecular microbiology - 1 Dec 2008

Connolly Keith, Rife Jason P, Culver Gloria

Abstract excerpt

While the general blueprint of ribosome biogenesis is evolutionarily conserved, most details have diverged considerably. A striking exception to this divergence is the universally conserved KsgA/Dim1p enzyme family, which modifies two adjacent adenosines in the terminal helix of small subunit ribosomal RNA (rRNA). While localization of KsgA on 30S subunits [small ribosomal subunits (SSUs)] and genetic interaction...

Topics

Cloning, Molecular
Cold Temperature
Escherichia coli
Escherichia coli Proteins
Gene Deletion
Gene Expression Regulation, Bacterial
Methylation
Methyltransferases
Mutation
Phenotype
RNA Processing, Post-Transcriptional

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Bacterial

RNA, Ribosomal, 16S

Ribosome Subunits, Small, Bacterial

Ribosomes

Source

Open in PubMed Open full text

Identifiers

PMID: 18990185
DOI: 10.1111/j.1365-2958.2008.06485.x
PMCID: PMC2709978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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