Article
The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3' end of 16S rRNA.
Proceedings of the National Academy of Sciences of the United States of America - 21 Jun 2011
Tu Chao, Zhou Xiaomei, Tarasov Sergey G, Tropea Joseph E, Austin Brian P, Waugh David S, Court Donald L, Ji Xinhua
Abstract excerpt
Era, composed of a GTPase domain and a K homology domain, is essential for bacterial cell viability. It is required for the maturation of 16S rRNA and assembly of the 30S ribosomal subunit. We showed previously that the protein recognizes nine nucleotides ( ) near the 3' end of 16S rRNA, and that this recognition stimulates GTP-hydrolyzing activity of Era. In all three kingdoms of life, the sequence and helix 45...
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