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Article

Male-specific association between a gamma-secretase polymorphism and premature coronary atherosclerosis.

PloS one - 1 Jan 2008

van Loo Karen M J, Dejaegere Tim, van Zweeden Martine, van Schijndel Jessica E, Wijmenga Cisca, Trip Mieke D, Martens Gerard J M

Abstract excerpt

BACKGROUND: Atherosclerosis is a common multifactorial disease resulting from an interaction between susceptibility genes and environmental factors. The causative genes that contribute to atherosclerosis are elusive. Based on recent findings with a Wistar rat model, we speculated that the gamma-secretase pathway may be associated with atherosclerosis. METHODOLOGY/PRINCIPAL FINDINGS: We have tested for association...

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Identifiers

PMID: 18987747
DOI: 10.1371/journal.pone.0003662
PMCID: PMC2573958

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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