Correlation between HIV-1 seropositivity and prevalence of a gamma-secretase polymorphism in two distinct ethnic populations.

doi:10.1002/jmv.21601

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Article

Correlation between HIV-1 seropositivity and prevalence of a gamma-secretase polymorphism in two distinct ethnic populations.

Journal of medical virology - 1 Nov 2009

van Loo Karen M J, van Schijndel Jessica E, van Zweeden Martine, van Manen Daniëlle, Trip Mieke D, Petersen Desiree C, Schuitemaker Hanneke, Hayes Vanessa M, Martens Gerard J M

Abstract excerpt

Susceptibility for human immunodeficiency virus type 1 (HIV-1) infection may be influenced by host genetics. Recent findings with a Wistar rat model raised the possibility that the gamma-secretase pathway may be associated with an individual's susceptibility to infection. A functional single-nucleotide polymorphism (SNP) in the gamma-secretase component APH1B (Phe217Leu; rs1047552) was therefore analyzed for...

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PMID: 19774691
DOI: 10.1002/jmv.21601

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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