Gender-specific association of ATP-binding cassette transporter 1 (ABCA1) polymorphisms with the risk of late-onset Alzheimer's disease.

doi:10.1016/j.neurobiolaging.2006.04.005

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Article

Gender-specific association of ATP-binding cassette transporter 1 (ABCA1) polymorphisms with the risk of late-onset Alzheimer's disease.

Neurobiology of aging - 1 Jun 2007

Sundar Purnima Desai, Feingold Eleanor, Minster Ryan L, DeKosky Steven T, Kamboh M Ilyas

Abstract excerpt

Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder caused by a complex interaction of genetic and environmental factors. Increasing evidence highlights a potential role for cholesterol in the pathophysiology of AD. The ABCA1 gene, located in close vicinity to the 9q linkage peaks identified by genome-wide AD linkage studies, plays an important role in cellular cholesterol efflux, and is...

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Identifiers

PMID: 16725228
DOI: 10.1016/j.neurobiolaging.2006.04.005

Genes

ABCA1
UBQLN1
APOE

Variants

rs2230806

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.