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Article

The CYP2C19 ultra-rapid metabolizer genotype influences the pharmacokinetics of voriconazole in healthy male volunteers.

European journal of clinical pharmacology - 1 Mar 2009

Wang Guo, Lei He-Ping, Li Zhi, Tan Zhi-Rong, Guo Dong, Fan Lan, Chen Yao, Hu Dong-Li, Wang Dan, Zhou Hong-Hao

Abstract excerpt

AIM: To study the pharmacokinetic characteristics of voriconazole in healthy Chinese male volunteers in relation to cytochrome P450 (CYP) 2C19 genotype status, including ultra-rapid metabolizers (URMs), homozygous extensive metabolizers (EMs), and poor metabolizers (PMs). METHOD: Twenty healthy Chinese male volunteers were recruited for the study. Of these, four were CYP2C19 heterozygous URMs (*1/*17), eight were...

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Identifiers

PMID: 18982321
DOI: 10.1007/s00228-008-0574-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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