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Impact of cytochrome P450 2C19 polymorphisms on the clinical efficacy and safety of voriconazole: an update systematic review and meta-analysis.

Pharmacogenetics and genomics - 1 Sept 2022

Zhang Ying, Hao Xu, Hou Kelu, Hu Lei, Shang Jingyuan, He Shiyu, Yang Changqing, Huang Lin, Feng Yufei

Abstract excerpt

OBJECTIVE: To assess the impact of cytochrome P450 (CYP) 2C19 polymorphisms on the clinical efficacy and safety of voriconazole. METHODS: We systematically searched PubMed, EMBASE, CENTRAL, ClinicalTrials.gov, and three Chinese databases from their inception to 18 March 2021 using a predefined search algorithm to identify relevant studies. Studies that reported voriconazole-treated patients and information on...

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Share to Chemical and Drug Induced Liver Injury
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35947050
DOI: 10.1097/FPC.0000000000000470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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