LRRK2 mutations in patients with Parkinson's disease from Peru and Uruguay.

doi:10.1016/j.parkreldis.2008.09.002

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Article

LRRK2 mutations in patients with Parkinson's disease from Peru and Uruguay.

Parkinsonism & related disorders - 1 Jun 2009

Mata Ignacio F, Cosentino Carlos, Marca Victoria, Torres Luis, Mazzetti Pilar, Ortega Olimpio, Raggio Victor, Aljanati Ruth, Buzó Ricardo, Yearout Dora, Dieguez Elena, Zabetian Cyrus P

Abstract excerpt

Variation in the leucine-rich repeat kinase 2 (LRRK2) gene represents the most common genetic determinant of Parkinson's disease (PD) identified to date. While the frequency and distribution of LRRK2 mutations have been well-studied in Europe and North America, few data are available from South America. To address this gap in knowledge, we screened two cohorts of patients with PD from Peru (n=240) and Uruguay...

Topics

Amino Acid Substitution
Carrier State
Cohort Studies
Family
Female
Genetic Markers
Genetic Variation
Humans
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Medical History Taking

Parkinson Disease

Peru

Polymorphism, Single Nucleotide

Protein Serine-Threonine Kinases

Uruguay

White People

Source

Open in PubMed

Identifiers

PMID: 18980856
DOI: 10.1016/j.parkreldis.2008.09.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-18980856-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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