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Article

Increased risk of suicide attempt in mood disorders and TPH1 genotype.

Journal of affective disorders - 1 Jun 2009

Galfalvy Hanga, Huang Yung-Yu, Oquendo Maria A, Currier Dianne, Mann J John

Abstract excerpt

BACKGROUND: The tryptophan hydroxylase 1 (TPH1) gene is reported to be associated with suicidal behavior. This has not been confirmed by prospective studies of suicide and clinical or biological mediators of this genetic risk have not been identified. METHODS: 343 subjects (Caucasian, African-American, Hispanic) presenting with a Major Depressive Episode were genotyped for polymorphisms A218C in intron 7 and...

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Source

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Identifiers

PMID: 18977032
DOI: 10.1016/j.jad.2008.09.019
PMCID: PMC4440550

Genes

TPH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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