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Article

Variability of the tryptophan hydroxylase gene: study in victims of violent suicide.

Psychiatry research - 30 Mar 2005

Stefulj Jasminka, Kubat Milovan, Balija Melita, Skavic Josip, Jernej Branimir

Abstract excerpt

Tryptophan hydroxylase (TPH), the enzyme controlling serotonin synthesis, is considered to be a potential contributor to the biological substrate of suicide. The association of the promoter (-7065CT) and intron 7 (218AC) polymorphisms, and the related haplotype, of the Tph1 gene with suicidal behavior was investigated in a sample of 160 victims of violent suicide and 284 healthy controls. All individuals were...

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Identifiers

PMID: 15808291
DOI: 10.1016/j.psychres.2004.04.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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