Article
The influence of gender, age, and RET polymorphisms on C-cell hyperplasia and medullary thyroid carcinoma.
Thyroid : official journal of the American Thyroid Association - 1 Dec 2008
Weinhaeusel Andreas, Scheuba Christian, Lauss Martin, Kriegner Albert, Kaserer Klaus, Vierlinger Klemens, Haas Oskar A, Niederle Bruno
Abstract excerpt
BACKGROUND: RET germline mutations predispose to the development of hereditary medullary thyroid carcinoma (hMTC). Several single nucleotide polymorphisms (SNPs) are described associated with sporadic MTC (sMTC). However, the findings regarding their influence on the clinical course and biological behavior of this disorder are discordant. To clarify the contradictory findings, we studied the association of...
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