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Article

Modulatory Role of Single Nucleotide Polymorphisms of Distinct Genetic Pathways on Clinical Behavior of Medullary Thyroid Carcinoma.

Asian Pacific journal of cancer prevention : APJCP - 1 May 2020

Mishra Vasudha, Kowtal Pradnya, Rane Pallavi, Sarin Rajiv

Abstract excerpt

BACKGROUND: Role of RET proto-oncogene as predisposing gene for Medullary Thyroid Carcinoma is well established which provides the basis for clinical management of patients. However clinical behavior of MTC varies considerably among patients. Several studies have investigated whether SNPs in low penetrance genes could modulate the clinical behavior of MTC but with conflicting or inconclusive results. The present...

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Identifiers

PMID: 32458635
DOI: 10.31557/APJCP.2020.21.5.1289
PMCID: PMC7541877

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