Article
C-cell hyperplasia and medullary thyroid carcinoma: clinicopathological and genetic correlations in 66 consecutive patients.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2003
Guyétant Serge, Josselin Nicolas, Savagner Fréderique, Rohmer Vincent, Michalak Sophie, Saint-André Jean-Paul
Abstract excerpt
Routine calcitonin (CT) assay programs and genetic testing for RET proto-oncogene mutations have consistently modified the management and understanding of C-cell proliferative disorders. We report a series of 66 consecutive patients with C-cell hyperplasia (CCH) or medullary thyroid carcinoma (MTC) observed in our institution within an 8-year time period. All the patients had a preoperative basal CT assay and an...
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