Distribution of RET Mutations and Evaluation of Treatment Approaches in Hereditary Medullary Thyroid Carcinoma in Turkey.

doi:10.4274/jcrpe.2219

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Article

Distribution of RET Mutations and Evaluation of Treatment Approaches in Hereditary Medullary Thyroid Carcinoma in Turkey.

Journal of clinical research in pediatric endocrinology - 5 Mar 2016

Aydoğan Berna İmge, Yüksel Bağdagül, Tuna Mazhar Müslüm, Navdar Başaran Mehtap, Akkurt Kocaeli Ayşen, Ertörer Melek Eda, Aydın Kadriye, Güldiken Sibel, Şimşek Yasin, Cihan Karaca Züleyha, Yılmaz Merve, Aktürk Müjde, Anaforoğlu İnan, Kebapçı Nur, Duran Cevdet, Taşlıpınar Abdullah, Kulaksızoğlu Mustafa, Gürsoy Alptekin, Dağdelen Selçuk, Erdoğan Murat Faik

Abstract excerpt

OBJECTIVE: This retrospective multicenter study, centrally conducted and supported by the Society of Endocrinology and Metabolism of Turkey, aimed to evaluate the impact of free RET proto-oncogene testing in medullary thyroid carcinoma (MTC) patients. Surgical timing, adequacy of the treatment, and frequency of prophylactic thyroidectomy (PTx) in mutation carriers were also assessed. METHODS: Genetic testing for...

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PMID: 26758973
DOI: 10.4274/jcrpe.2219
PMCID: PMC4805043

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