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Article

Polymorphisms in exon 13 and intron 14 of the RET protooncogene: genetic modifiers of medullary thyroid carcinoma?

The Journal of clinical endocrinology and metabolism - 1 Nov 2005

Baumgartner-Parzer S M, Lang R, Wagner L, Heinze G, Niederle B, Kaserer K, Waldhäusl W, Vierhapper H

Abstract excerpt

CONTEXT: Single-nucleotide polymorphisms (SNPs) of the RET protooncogene (RET) could modify disease susceptibility and clinical phenotype in patients with sporadic or familial medullary thyroid carcinoma (FMTC). OBJECTIVE/DESIGN OF THE STUDY: Because frequencies of RET SNPs have not yet been evaluated in patients with elevated serum concentrations of calcitonin (hCt), a biochemical marker for medullary thyroid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16118333
DOI: 10.1210/jc.2005-1278

Genes

RET

Variants

rs2472737
rs2472737
rs2472737
rs2472737

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphisms in exon 13 and intron 14 of the RET protooncogene: genetic modifiers of medullary thyroid carcinoma?PMID 16118333Read ↗

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Frequency of RET Proto-Oncogene Mutations in Patients with Normal and with Moderately Elevated Pentagastrin-Stimulated Serum Concentrations of CalcitoninSemantic proximity Read ↗

Single nucleotide polymorphisms act as modifiers and correlate with the development of medullary and simultaneous medullary/papillary thyroid carcinomas in 2 large, non-related families with the RET V804M proto-oncogene mutation.Semantic proximity Read ↗

The influence of gender, age, and RET polymorphisms on C-cell hyperplasia and medullary thyroid carcinoma.Semantic proximity Read ↗

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