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Article

Histopathological and molecular studies in patients with goiter and hypercalcitoninemia: reactive or neoplastic C-cell hyperplasia?

Endocrine-related cancer - 1 Jun 2007

Verga Uberta, Ferrero Stefano, Vicentini Leonardo, Brambilla Tatiana, Cirello Valentina, Muzza Marina, Beck-Peccoz Paolo, Fugazzola Laura

Abstract excerpt

The cut-off values able to differentiate between reactive or neoplastic C-cell hyperplasia (CCH) or to predict sporadic medullary thyroid cancer (MTC) are still debated both for basal and stimulated calcitonin (bCT and sCT). In the present study, the prevalence and the histological patterns of CCH in 15 patients with multinodular goiter (MNG), bCT>10 pg/ml and sCT levels >50 pg/ml were studied. As controls, 16...

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PMID: 17639053
DOI: 10.1677/ERC-06-0053

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RET

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Source receipt: pubmed, retrieved 7 Sept 2026.

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