Article
The protonation state of the cross-linked tyrosine during the catalytic cycle of cytochrome c oxidase.
The Journal of biological chemistry - 12 Dec 2008
Gorbikova Elena A, Wikström Mårten, Verkhovsky Michael I
Abstract excerpt
Cytochrome c oxidase is the terminal complex of the respiratory chain in mitochondria and some aerobic bacteria and is responsible for most of the O(2) consumption in biology. The key reaction in the catalysis of O(2) reduction is O-O bond scission that requires four electrons and a proton. In our recent work (Gorbikova, E. A., Belevich, I., Wikstrom, M., and Verkhovsky, M. I. (2008) Proc. Natl. Acad. Sci. U. S....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.