Article
Molecular characterization of a region of DNA associated with mutations at the agouti locus in the mouse.
Proceedings of the National Academy of Sciences of the United States of America - 15 Sept 1991
Bultman S J, Russell L B, Gutierrez-Espeleta G A, Woychik R P
Abstract excerpt
Molecular characterization of a radiation-induced agouti (a)-locus mutation has resulted in the isolation of a segment of DNA that maps at or near the a locus on chromosome 2 in the mouse. This region of DNA is deleted in several radiation- or chemical-induced homozygous-lethal a-locus mutations...
Topics
- Animals
- Base Sequence
- Blotting, Southern
- Chromosome Deletion
- Chromosome Inversion
- Cloning, Molecular
- Mice
- Molecular Sequence Data
- Mutation
- Restriction Mapping
- Skin Pigmentation